Shaanxi Yongyuan Bio-Tech Co.,Ltd

Product Name: Genistein

Botanical Source: Genista tinctoria Linn, Sophora subprostrala Chun et T.Chen, S.japonica L.

Specification: 98% HPLC

CAS NO.: 446-72-0

Molecular formula: C15H10O5

Molecular weight: 270.2369

Appearance: Light yellow to White powder

Place of origin: China

Description: Genistein is a phytoestrogen and belongs to the category of isoflavones.Genistein

was first isolated in 1899 from the Dyer's broom, Genista tinctoria; hence, the chemical name. The compound structure was established in 1926 when it was found to be identical with prunetol. It was chemically synthesized in 1928.

Main function

1.Anti-cancer. The main known activity of genistein is tyrosine kinase inhibitor, mostly of epidermal growth factor receptor (EGFR). Genistein can fight against cancer by inhibiting the activity of protein tyrosine kinase and inhibits the phosphorylation of intracellular proteins.

2.Antioxidant. Genistein may act as a direct antioxidant, similar to many other isoflavones, and thus may alleviate damaging effects of free radicals in tissues.

3. Effects on atherosclerotic. Genistein protects against pro-inflammatory factor-induced vascular endothelial barrier dysfunction and inhibits leukocyte-endothelium interaction, thereby modulating vascular inflammation, a major event in the pathogenesis of atherosclerosis.

4.Genistein and other isoflavones have been identified as angiogenesis inhibitors and found to inhibit the uncontrolled cell growth of cancer, most likely by inhibiting the activity of the substance in the body that regulate cell division and cell survival (growth factors).

5.Genistein was found to be the major isoflavone responsible for the deworming property. Genistein was subsequently demonstrated to be highly effective against intestinal parasites.

6.Genistein can bind to estrogen receptors, play a weak estrogen-like effect, increase bone density, and prevent bone loss, to treat osteoporosis.

Application

1. Applied in pharmaceutical field, it can be made into suppository, lotion, injection, tablets,

capsules, etc.
2. Applied in health product field, it is mainly used in female health product and health medicine

for delaying aging and preventing hematological disease and cancer.

Storage: Store at a cool&dry place.Protect from light, moisture and pest infestation.

Shelf life: 2 years when properly stored.